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Science Reducept

The science behind the Reducept Method

The Reducept Method trains the brain to reduce pain. For this we use scientific knowledge about digital training, pain education and psychology. By cleverly combining these three, we have developed our unique Method.

Research pipeline

  1. Study on the Efficacy, Acceptability, Tolerability and Feasibility of Reducept on Improving the Quality of Life in Non-specific Chronic Low-back Pain Patients
  • Focus: Lower Back Pain
  • Details: RCT / N=40
  • Research partner: Radboud/Rijnstate
  1. Results and experiences of long term reducept training in a physiotherapy setting
  • Focus: Chronic Pain
  • Details: Feasibility / N=55
  • Research partner: Revalidatie Friesland/Hogeschool Utrecht/ Spectrum Physiotherapy
  1. Virtual Reality in the Treatment of Chronic Pain
  • Focus: Lower Back Pain
  • Details: Pilot Study: Multiple baseline ABA design / N=tbd
  • Research partner: Radboud/CWZ/Klimmendaal/Dongers Institute
  1. VR-MAP: A Pilot on Virtual Reality in Management of Adhesion-related Chronic Abdominal Pain
  • Focus: Chronic Abdominal Pain
  • Details: Pilot Study / N=10
  • Research partner: Radboud UMC
  1. Reducing Awakenings and Increasing Sleep Efficiency With Virtual Reality in Patients Suffering From
  • Focus: Diabetic Polyneuropathy
  • Details: Double-Blind Randomized Experimental single centre study / N=20
  • Research partner: UMC Brussel (BE)
  1. Pain care at home (zorg experiment)
  • Focus: Chronic Pain
  • Details: Pilot Study / N=20
  • Research partner: Maasstad Ziekenhuis

What we treat

Reducept is a digital training method designed for people who have been struggling with pain for a long time. The training works best as a supplement to the standard consultations and exercises prescribed to patients with the following conditions:

  • Tense muscles, lack of energy, limited mobility, pressure, aching;
  • Lower back pain, frequent headaches, neck pain, shoulder pain;
  • Joint pain, arthritis pain, rheumatism;
  • Breakthrough pain;
  • Cancer pain, malignant pain;
  • Nerve pain, nerve damage pain, Neuropathy, neuropathic pain, MS, diabetic polyneuropathy;
  • Irritable bowel syndrome, hernia, fibromyalgia, nociceptive pain;
  • Post-operative pain;
  • Allodynia, hyperalgesia, paresthesia, hyperpathia, CRPS 1, CRPS 2, phantom limb pain.

For those who like to know and understand

There is a lot of evidence that digital training decreases pain. Together with leading institutions, we have scientifically researched that the Reducept Method has a significant effect on pain levels.

Download White Paper
Reducept Brain mini game

These papers inspired our approach

“...several studies suggest that VR can be effective as a complementary adjunct or alternative non-pharmacologic analgesic in a range of pain-inducing procedures and in management of chronic pain.”

Ahmadpour et al. (2019)

“...the introduction of the biopsychosocial model of pain during the past decade stimulated the development of more therapeutically effective and cost-effective interdisciplinary chronic pain management programs”

Gatchel et al, (2014)

“"The usefulness and importance of serious games and simulations in learning and behavior change for health and health-related issues are widely recognized."”

Kuipers et al (2017)

“It appears to be a wicked problem to design serious games that retain the unique and motivational characteristics that make games as a learning tool interesting in the first place.”

Kuipers et al (2019)

“For chronic MSK pain disorders, there is compelling evidence that an educational strategy addressing neurophysiology and neurobiology of pain can have a positive effect on pain, disability, catastrophization, and physical performance. ”

Louw et al (2011)

“"...acceptance and commitment therapy (ACT) and mindfulness-based approaches, [...] may hold potential for future progress."”

McCracken & Vowles (2014)

“"We contend that [explaining pain] is grounded in strong theoretical frameworks, that its targeted effects are biologically plausible, and that available behavioral evidence is supportive."”

Moseley & Butler (2015)

“"Our main results showed a significant effect of psychoeducation/physiotherapy on control, harm, and medical cure [Survey of Pain Attitudes] subscales..."”

Vanhaudenhuyse et al (2018)

“"CBT is effective in altering mood and catastrophising outcomes, when compared with treatment as usual/waiting list, with some evidence that this is maintained at six months."”

Williams, Eccleston, & Morley (2012)



  1. Ahmadpour, N., Randall, H., Choksi, H., Gao, A., Vaughan, C., & Poronnik, P. (2019). Virtual Reality interventions for acute and chronic pain managementThe international journal of biochemistry & cell biology114, 105568.
  2. Gatchel, R. J., McGeary, D. D., McGeary, C. A., & Lippe, B. (2014). Interdisciplinary chronic pain management: past, present, and futureAmerican Psychologist69(2), 119.
  3. Kuipers, D. A., Terlouw, G., Wartena, B. O., van't Veer, J. T., Prins, J. T., & Pierie, J. P. E. (2017). The role of transfer in designing games and simulations for health: systematic review. JMIR Serious Games, 5(4), e7880.
  4. Kuipers, D. (2019). Design for Transfer: figural transfer through metaphorical recontextualization in Games for Health.
  5. Louw, A., Diener, I., Butler, D. S., & Puentedura, E. J. (2011). The effect of neuroscience education on pain, disability, anxiety, and stress in chronic musculoskeletal painArchives of physical medicine and rehabilitation92(12), 2041-2056.
  6. McCracken, L. M., & Vowles, K. E. (2014). Acceptance and commitment therapy and mindfulness for chronic pain: Model, process, and progressAmerican Psychologist69(2), 178.
  7. Moseley, G. L., & Butler, D. S. (2015). Fifteen years of explaining pain: the past, present, and futureThe Journal of Pain16(9), 807-813.
  8. Smits, M.L.M., Vries, de M., Garms, L, Delcliseur, H., Kallewaard, J.W.,  Geurts, J., Lier, E.J., & van Goor, H. (2019). Efficacy, Acceptability, Tolerability and Feasibility of a Therapeutic Virtual Reality Application on Improving the Quality of Life in Non specific Chronic Low back Pain Patients. Unpublished clinical trial.
  9. Vanhaudenhuyse, A., Gillet, A., Malaise, N., Salamun, I., Grosdent, S., Maquet, D., ... & Faymonville, M. E. (2018). Psychological interventions influence patients' attitudes and beliefs about their chronic painJournal of traditional and complementary medicine8(2), 296-302.
  10. de C Williams, A. C., Eccleston, C., & Morley, S. (2012). Psychological therapies for the management of chronic pain (excluding headache) in adultsCochrane database of systematic reviews, (11).